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| CAS号 | 2095719-92-7 | 货号 | BCP32082 |
| 中文名 | ASTX-029 | ||
| 英文名 | ASTX-029 | ||
| 中文别名 | |||
| 英文别名 | ASTX 029;ASTX 029;ERK1/2 inhibitor 2; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C29H31ClFN5O5 | 分子量 | 584.04 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | ASTX029 is a synthetic small molecule inhibitor of extracellular signal-regulated kinases (ERKs) 1/2. ASTX029 has not been previously evaluated in human subjects. The Phase 1 portion of this study will assess safety and determine the maximum tolerated dose, the recommended Phase 2 dose (RP2D), and the recommended dosing regimen of ASTX029 administered orally. The Phase 2 portion will assess preliminary clinical activity in tumors characterized by gene aberrations in the mitogen-activated protein kinase (MAPK) signal pathway that may confer sensitivity to ASTX029. | ||
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