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CAS号 | 724424-43-5 | 货号 | BCP46785 |
中文名 | CE-224535 | ||
英文名 | CE-224535 | ||
中文别名 | |||
英文别名 | CE 224535; CE224535; CE-224,535; CE 224,535; CE224,535; | ||
SMILES | COC(N1C(=O)C=NN(C1=O)C2=CC(=C(C=C2)Cl)C(=O)NCC3(CCCCCC3)O)O | ||
化学名称 | |||
分子式 | C22H29ClN4O6 | 分子量 | 480.94 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | CE-224535 is a P2X7 receptor antagonist potentially for the treatment of rheumatoid arthritis and osteoarthritis. Clinical trials in 2012 showed that CE-224,535 was not efficacious, compared with placebo, for the treatment of RA in patients with an inadequate response to MTX. CE-224,535 demonstrated an acceptable safety and tolerability profile. |
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