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| CAS号 | 724708-21-8 | 货号 | BCP46034 |
| 中文名 | Chk2 Inhibitor | ||
| 英文名 | Chk2 Inhibitor | ||
| 中文别名 | |||
| 英文别名 | Hymenialdisine Analogue 1;CHK2;SC-203885; SC 203885; SC203885; | ||
| SMILES | C1CNC(=O)C2=NC3=CC=CC=C3C2=C1C4=C(N=C(N4)N)O | ||
| 化学名称 | |||
| 分子式 | C15H13N5O2 | 分子量 | 295.3 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Chk2 inhibitor is an inhibitor of checkpoint kinase 2 (Chk2; IC50 = 13.5 nM). Chk2 inhibitor enhances survival of 184B5, but not MDA-MB-231, cells following ionizing radiation and inhibits cell cycle arrest at the G2 stage induced by ionizing radiation in 184B5 cells. It also inhibits the production of IL-2 in Jurkat cells, the production of TNF-α in LPS-stimulated THP-1 cells and the growth of CEM leukemia T cells. | ||
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