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| CAS号 | 1260533-36-5 | 货号 | BCP25132 |
| 中文名 | TAS-116 | ||
| 英文名 | TAS-116 | ||
| 中文别名 | |||
| 英文别名 | TAS116;TAS 116; Pimitespib; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C25H26N8O | 分子量 | 454.54 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | TAS-116 is a potent and selective inhibitor of heat shock protein 90 (Hsp90) subtypes alpha and beta, with potential antineoplastic and chemo/radiosensitizing activities. TAS-116 specifically binds to and inhibits the activity of Hsp90 alpha and beta; this results in the proteasomal degradation of oncogenic client proteins, which inhibits client protein dependent-signaling, induces apoptosis, and inhibits the proliferation of cells overexpressing HSP90alpha/beta. | ||
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