参考资料
在线咨询
购买咨询即时询价 ×
* 必填项
请填妥以下表格,您将在一分钟内得到邮件机器人给你的报价。
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS号 | 2355377-13-6 | 货号 | BCP42338 |
| 中文名 | DDO-5936 | ||
| 英文名 | DDO-5936 | ||
| 中文别名 | |||
| 英文别名 | DDO 5936; DDO5936; | ||
| SMILES | CC1=CC(=C(C(=C1)C)S(=O)(=O)N(CC(=O)O)C2=CC=C(C=C2)NC3=NC(=NC=C3)N4CCCC4)C | ||
| 化学名称 | |||
| 分子式 | C25H29N5O4S | 分子量 | 495.59 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | DDO-5936 is a potent PPI inhibitor targeting Hsp90-Cdc37 protein-protein interaction (PPI) as Orally Active Inhibitors for the Treatment of Colorectal Cancer. DDO-5936 disrupted the Hsp90-Cdc37 PPI both in vitro and in vivo via binding to a previously unknown site on Hsp90 involving Glu47, one of the binding determinants for the Hsp90-Cdc37 PPI, leading to selective down-regulation of Hsp90 kinase clients in HCT116 cells. In addition, inhibition of Hsp90-Cdc37 complex formation by DDO-5936 resulted in a remarkable cyclin-dependent kinase 4 decrease and consequent inhibition of cell proliferation through Cdc37-dependent cell cycle arrest. | ||
在购买和使用瀚香生物产品的过程中，您遇到的任何问题，都可以咨询我们的免费热线：400-099-8200，或者和我们的客服 
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
。 我们竭诚解决您的一切疑惑，保证您的舒心顺畅。
Tags:DDO-5936 供应商,DDO-5936 购买,DDO-5936 生产,DDO-5936 批量,DDO-5936 供应,DDO-5936 订购,DDO-5936 采购