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CAS号 | 343351-67-7 | 货号 | BCP45754 |
中文名 | NSC697923 | ||
英文名 | NSC697923 | ||
中文别名 | |||
英文别名 | NSC 697923; NSC-697923; | ||
SMILES | CC1=CC=C(C=C1)S(=O)(=O)C2=CC=C(O2)[N+](=O)[O-] | ||
化学名称 | |||
分子式 | C11H9NO5S | 分子量 | 267.26 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | NSC697923 is a potent UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13) inhibitor. NSC697923 induces neuroblastoma (NB) cell death via promoting nuclear importation of p53 in p53 wild-type NB cells. NSC697923 also induces cell death in p53 mutant NB cells by activation of JNK-mediated apoptotic pathway. NSC697923 inhibits DNA damage and NF-κB signaling. Antitumor activity. |
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