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| CAS号 | 2259648-80-9 | 货号 | BCP32805 |
| 中文名 | CC-92480 | ||
| 英文名 | CC-92480 | ||
| 中文别名 | |||
| 英文别名 | CC 92480; CC92480; | ||
| SMILES | N#CC1=CC=C(N2CCN(CC3=CC=C(COC4=CC=CC5=C4CN([C@@H](CC6)C(NC6=O)=O)C5=O)C=C3)CC2)C(F)=C1 | ||
| 化学名称 | |||
| 分子式 | C32H30FN5O4 | 分子量 | 567.62 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | CC-92480 is a cereblon E3 ubiquitin ligase modulating agent with potential immunomodulating and antineoplastic activities. CC-92480 specifically binds to cereblon (CRBN), thereby affecting the ubiquitin E3 ligase activity, and targeting certain substrate proteins for ubiquitination. This induces proteasome-mediated degradation of certain transcription factors, some of which are transcriptional repressors in T cells. This leads to modulation of the immune system, including activation of T lymphocytes, and downregulation of the activity of other proteins, some of which play key roles in the proliferation of certain cancer cell types. | ||
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