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Thalidomide 结构式

沙利度胺

参考资料 仅供科学研究,不可用于个人用途。
货号 :BCP19772CAS号 :50-35-1纯度:98%
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  • 基本信息与产品描述
CAS号 50-35-1 货号 BCP19772
中文名 沙利度胺
英文名 Thalidomide
中文别名
英文别名 Thalomid;
SMILES
化学名称
分子式 C13H10N2O4 分子量 258.23
纯度 98% 配送 惯例下常温包邮
产品描述 Thalidomide is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis.
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