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CAS号 | 50-35-1 | 货号 | BCP19772 |
中文名 | 沙利度胺 | ||
英文名 | Thalidomide | ||
中文别名 | |||
英文别名 | Thalomid; | ||
SMILES | |||
化学名称 | |||
分子式 | C13H10N2O4 | 分子量 | 258.23 |
纯度 | 98% | 配送 | 惯例下常温包邮 |
产品描述 | Thalidomide is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis. |
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