优立替尼盐酸盐新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP30834CAS号：1956366-10-1纯度：98%

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CAS号	1956366-10-1	货号	BCP30834
中文名	优立替尼盐酸盐
英文名	Ulixertinib hydrochloride
中文别名	盐酸优立替尼;
英文别名	Ulixertinib HCl;BVD-523 HCl;BVD 523 HCl;BVD523 HCl;VRT752271 HCl;VRT752271 HCl; VRT 752271 HCl;Ulixertinib HCl salt;
SMILES	CC(C)NC1=NC=C(C(=C1)C2=CNC(=C2)C(=O)NC(CO)C3=CC(=CC=C3)Cl)Cl.Cl
化学名称
分子式	C21H23Cl3N4O2	分子量	469.79
纯度	98%	配送	惯例下常温包邮
产品描述	Ulixertinib, also known as BVD-523 and VRT752271, is an inhibitors of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.

优立替尼盐酸盐 新