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MK-3903 结构式

MK-3903

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货号 :BCP29075CAS号 :1219737-12-8纯度:98%
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  • 基本信息与产品描述
CAS号 1219737-12-8 货号 BCP29075
中文名 MK-3903
英文名 MK-3903
中文别名
英文别名 MK 3903; MK3903;
SMILES
化学名称
分子式 C27H19ClN2O3 分子量 454.91
纯度 98% 配送 惯例下常温包邮
产品描述 MK-3903 is a potent and selective AMPK activator (EC50 = 8 nM). MK-3903 exhibited robust target engagement in mouse liver following oral dosing, leading to improved lipid metabolism and insulin sensitization in mice. Chronic oral administration of MK-3903 robustly increased ACC phosphorylation in liver with more modest effects in skeletal muscle. Treatment of various mouse models with MK-3903 resulted in expected alterations in lipid metabolism and improvements in a measure of insulin sensitization.
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