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Rosiglitazone 结构式

罗格列酮

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货号 :BCP03047CAS号 :122320-73-4纯度:98%
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  • 基本信息与产品描述
CAS号 122320-73-4 货号 BCP03047
中文名 罗格列酮
英文名 Rosiglitazone
中文别名
英文别名 Avandia;BRL-49653;BRL 49653;BRL49653; HSDB 7555; HSDB-7555; HSDB7555; TDZ 01; TDZ-01; TDZ01;
SMILES
化学名称
分子式 C18H19N3O3S 分子量 357.43
纯度 98% 配送 惯例下常温包邮
产品描述 Rosiglitazone (Avandia) has recently been identified as a high-affinity ligand for PPARγ, a nuclear hormone receptor that is abundantly expressed in adipocytes and plays a central role as a regulator of terminal adipocyte differentiation. Rosiglitazone (Avandia) acts primarily by increasing insulin sensitivity. Rosiglitazone (Avandia) improves glycemic control while reducing circulating insulin levels. Rosiglitazone (Avandia) is a member of the thiazolidinedione class of drugs. They reduce glucose, fatty acid, and insulin blood concentrations. They work by binding to the peroxisome proliferator-activated receptors (PPARs). Thiazolidinediones enter the cell, bind to the nuclear receptors, and affect the expression of DNA. Rosiglitazone (Avandia, BRL-49653) also appears to have an anti-inflammatory effect in addition to its effect on insulin resistance.
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