雷西莫特盐酸盐新

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货号：BCP38086CAS号：1313757-36-6纯度：98%

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CAS号	1313757-36-6	货号	BCP38086
中文名	雷西莫特盐酸盐
英文名	Resiquimod HCl
中文别名
英文别名	R-848; R 848; R848; S 28463; S-28463; S28463; VML-600; VML600; VML 600;
SMILES	CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
化学名称
分子式	C17H23ClN4O2	分子量	350.85
纯度	98%	配送	惯例下常温包邮
产品描述	Resiquimod is a n imidazoquinolinamine Toll-like receptor (TLR) agonist with potential immunostimulatory activity. Resiquimod binds to and activates TLRs 7 and 8, mainly on dendritic cells (DCs), macrophages, and B-lymphocytes, which results in the activation of the TLR signaling pathway and nuclear translocation of the transcription activator NF-kB another transcription factors; subsequently, the production of cytokines, especially interferon-alpha (INF-a), increases, enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans cells, which may result in enhanced activation of T-lymphocytes.

雷西莫特盐酸盐 新