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Carboxyamidotriazole Orotate 结构式

Carboxyamidotriazole Orotate

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货号 :BCP34906CAS号 :187739-60-2纯度:98%
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  • 基本信息与产品描述
CAS号 187739-60-2 货号 BCP34906
中文名 Carboxyamidotriazole Orotate
英文名 Carboxyamidotriazole Orotate
中文别名
英文别名 L-651582 Orotate; CAI Orotate; L 651582; L-651582; L651582; NSC 609974; NSC609974; NSC-609974;
SMILES C1=CC(=CC=C1C(=O)C2=C(C=C(C=C2Cl)CN3C(=C(N=N3)C(=O)N)N)Cl)Cl.C1=C(NC(=O)NC1=O)C(=O)O
化学名称
分子式 C23H16Cl3IN7O6 分子量 580.76
纯度 98% 配送 惯例下常温包邮
产品描述 Carboxyamidotriazole orotate is t he orotate salt form of carboxyamidotriazole (CAI), an orally bioavailable small molecule with potential antiangiogenic and antiproliferative activities. Carboxyamidotriazole binds to and inhibits non-voltage-operated calcium channels, blocking both Ca2+ influx into cells and Ca2+ release from intracellular stores, resulting in the disruption of calcium channel-mediated signal transduction. CAI inhibits PI3 activity and vascular endothelial growth factor (VEGF) signaling. This may inhibit endothelial proliferation, tumor cell growth, invasion and metastasis.
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