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Phlorizin 结构式

Phlorizin

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货号 :BCP29914CAS号 :60-81-1纯度:98%
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  • 基本信息与产品描述
CAS号 60-81-1 货号 BCP29914
中文名 Phlorizin
英文名 Phlorizin
中文别名
英文别名 Phloridzin; phloretin-2'-β-D-glucopyranoside; AI3-19835; NSC 2833; Phloretin 2'-glucoside; Phloretin-2'-O-beta-glucoside; Phlorizoside; Phlorrhizin;
SMILES C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2OC3C(C(C(C(O3)CO)O)O)O)O)O)O
化学名称
分子式 C21H24O10 分子量 436.41
纯度 98% 配送 惯例下常温包邮
产品描述 Phlorizin, also referred to as phloridzin, is a glucoside of phloretin, a dihydrochalcone, a family of bicyclic flavonoids, which in turn is a subgroup in the diverse phenylpropanoid synthesis pathway in plants. Phlorizin is a competitive inhibitor of SGLT1 and SGLT2 because it competes with D-glucose for binding to the carrier; this reduces renal glucose transport, lowering the amount of glucose in the blood. Phlorizin was studied as a potential pharmaceutical treatment for type 2 diabetes, but has since been superseded by more selective and more promising synthetic analogs, such as canagliflozin and dapagliflozin.
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