马来酸依那普利新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP21378CAS号：76095-16-4纯度：98%

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CAS号	76095-16-4	货号	BCP21378
中文名	马来酸依那普利
英文名	Enalapril Maleate
中文别名
英文别名	Maleate, Enalapril; MK 421; MK-421; MK421;
SMILES	CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CCCC2C(=O)O.C(=CC(=O)O)C(=O)O
化学名称
分子式	C24H32N2O9	分子量	492.52
纯度	98%	配送	惯例下常温包邮
产品描述	Enalapril maleate is an effective and potent angiotensin-converting enzyme inhibitor that is used to treat hypertension and heart failure. The compound has been used to study diabetic angiopathy in diabetic rats and inhibition of ACE in hog plasma. ACE inhibitors disturb the enin-angiotensin- aldosterone system. As a prodrug, enalapril is converted by de-esterification into its active form enalaprilat. Enalaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Enalapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.

马来酸依那普利 新