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| CAS号 | 872141-23-6 | 货号 | BCP21063 |
| 中文名 | Way255348 | ||
| 英文名 | Way255348 | ||
| 中文别名 | |||
| 英文别名 | WAY-255348; WAY 255348; | ||
| SMILES | N#CC1=CC=C(C2=CC3=C(NC(C3(C)C)=O)C(F)=C2)N1C | ||
| 化学名称 | |||
| 分子式 | C16H14FN3O | 分子量 | 283.3 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | WAY-255348 is a potent nonsteroidal progesterone receptor (PR) antagonist. WAY-255348 inhibits the activity of progesterone. WAY-255348 achieves antagonist activity by binding to and subsequently preventing progesterone-induced nuclear accumulation, phosphorylation and promoter interactions of the PR. WAY-255348 bound PR conformation was similar to that of a progesterone agonist-bound PR and distinct from steroidal antagonist-bound PR conformations. WAY-255348 inhibits PR action through a novel molecular mechanism that is distinct from previously studied PR modulators and may be a useful tool to further understanding of PR signaling pathways. | ||
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