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| CAS号 | Mmethanesulfonate | 货号 | BCP29839 |
| 关联产品 | 1092970-12-1（莫非赛定） | ||
| 中文名 | 甲磺酸莫非赛定 | ||
| 英文名 | Morphothiadin methanesulfonate | ||
| 中文别名 | |||
| 英文别名 | GLS4 methanesulfonate; GLS-4 methanesulfonate; GLS 4 methanesulfonate; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C22H26BrFN4O6S2 | 分子量 | 605.49 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Morphothiadin, also known GLS4, is a potent and selective inhibitor of hepatitis B virus. GLS4 demonstrated potent inhibitory activities in HBV HepG2.2.15 cell assay with an EC50 value of 1nM, and it also exhibited high potency against various drug-resistant HBV viral strains with EC50 values in the range of 10-20nM, more potent than the typical HBV polymerase inhibitors such as lamivudine, telbivudine, and entecavir. Pharmacokinetic profiles of GLS4 were favorable and safety evaluation including acute toxicity and repeated toxicity study indicated that GLS4 was safe enough to support clinical experiments in human. | ||
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