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| CAS号 | 1019331-10-2 | 货号 | BCP06882 |
| 中文名 | S0859 | ||
| 英文名 | S0859 | ||
| 中文别名 | |||
| 英文别名 | S 0859;S-0859; | ||
| SMILES | |||
| 化学名称 | |||
| 分子式 | C29H24ClN3O3S | 分子量 | 530.04 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | S0859 is a selective, high-affinity generic NBC inhibitor, potentially important for probing the transporter's functional role in heart and other tissues. S0859 reversibly inhibited NBC-mediated pH(i) recovery (K (i)=1.7 microM, full inhibition at approximately 30 microM). In HEPES-buffered superfusates, NHE-mediated pH(i) recovery was unaffected by 30 microM S0859. With CO(2)/HCO(3) (-) buffer, pH(i) recovery from intracellular alkalosis (mediated by Cl(-)/HCO(3) (-) and Cl(-)/OH(-) exchange) was also unaffected. | ||
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