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Gemcitabine hydrochloride 结构式

盐酸吉西他滨

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货号 :BCP04160CAS号 :122111-03-9纯度:98%
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  • 基本信息与产品描述
CAS号 122111-03-9 货号 BCP04160
中文名 盐酸吉西他滨
英文名 Gemcitabine hydrochloride
中文别名 盐酸吉西他宾;吉西他宾盐酸盐;
英文别名 Gemcitabine HCl; LY188011 hydrochloride;LY 188011 hydrochloride;LY-188011 hydrochloride;
SMILES
化学名称
分子式 C9H12ClF2N3O4 分子量 299.66
纯度 98% 配送 惯例下常温包邮
产品描述 Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Treatment of BxPC-3 cells with low dose Gemcitabine for 48 hours results in a dose-dependent increase in NF-κB binding. In contrast, NF-κB DNA binding is decreased in BxPC-3 cells treated with the higher Gemcitabine doses for 48 h; however, 24-h treatment with these higher doses increases NF-κB binding in BxPC-3 cells.
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