盐酸环胞苷新

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货号：BCP12373CAS号：10212-25-6纯度：98%

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CAS号	10212-25-6	货号	BCP12373
中文名	盐酸环胞苷
英文名	Ancitabine hydrochloride
中文别名	环胞甙盐酸盐;
英文别名	Cyclocytidine hydrochloride;Cyclocytidine HCl;Cyclo-CMP hydrochloride;
SMILES	C1=CN2C3C(C(C(O3)CO)O)OC2=NC1=N.Cl
化学名称
分子式	C9H12ClN3O4	分子量	261.66
纯度	98%	配送	惯例下常温包邮
产品描述	Ancitabine Hydrochloride is the hydrochloride salt of a cytarabine congener prodrug with antineoplastic activity. Upon administration, ancitabine is slowly hydrolyzed into cytarabine. Subsequently, cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycle. Cytarabine agent also inhibits DNA polymerase, resulting in a decrease in DNA replication and repair. Compared to cytarabine, a more prolonged, consistent cytarabine-mediated therapeutic effect may be achieved with ancitabine because of the slow hydrolytic conversion of ancitabine to cytarabine.

盐酸环胞苷 新