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| CAS号 | 1316755-16-4 | 货号 | BCP24001 |
| 中文名 | EMA401 | ||
| 英文名 | EMA401 | ||
| 中文别名 | |||
| 英文别名 | Olodanrigan; EMA 401 ; EMA-401; | ||
| SMILES | COC1=C(C2=C(CN(C(C2)C(=O)O)C(=O)C(C3=CC=CC=C3)C4=CC=CC=C4)C=C1)OCC5=CC=CC=C5 | ||
| 化学名称 | |||
| 分子式 | C32H29NO5 | 分子量 | 507.58 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | EMA401, a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG neuron hyperexcitability and sprouting of DRG neurons. target: AT2R In vivo: AngII induces p38, p42/p44 mitogen activated protein kinase (MAPK) activation, neurite outgrowth in adult rat DRG neurons, and sensitization of adult rat and human DRG neurons that is blocked by EMA401. Inhibits capsaicin responses in cultured hDRG neurons. | ||
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