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Pleconaril 结构式

普可那利

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货号 :BCP20819CAS号 :153168-05-9纯度:98%
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  • 基本信息与产品描述
CAS号 153168-05-9 货号 BCP20819
中文名 普可那利
英文名 Pleconaril
中文别名
英文别名 SR-263843; SR-63843; VP-63843; Win-63843; SR263843; SR63843; VP63843; Win63843; SR 263843; SR 63843; VP 63843; Win 63843;
SMILES CC1=C(OCCCC2=CC(C)=NO2)C(C)=CC(C3=NOC(C(F)(F)F)=N3)=C1
化学名称
分子式 C18H18F3N3O3 分子量 381.35
纯度 98% 配送 惯例下常温包邮
产品描述 Pleconaril is an antiviral drug potentially for the treatment of enterovirus infection and asthma. Pleconaril, administered either orally or intranasally, is active against viruses in the Picornaviridae family, including Enterovirus and Rhinovirus.It has shown useful activity against the dangerous strain enterovirus D68. Pleconaril binds to a hydrophobic pocket in the VP1 protein. Pleconaril has been shown in viral assembly to associate with viral particles.[9] Through noncovalent, hydrophobic interactions compounds can bind to the hydrophobic pocket. Amino acids in positions Tyr152 and Val191 are a part of the VP1 drug binding pocket.
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