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NSC 146109 hydrochloride 结构式

NSC 146109 hydrochloride

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货号 ：BCP48536CAS号 ：59474-01-0纯度：98%
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  • 基本信息与产品描述
CAS号 59474-01-0 货号 BCP48536
中文名 NSC 146109 hydrochloride
英文名 NSC 146109 hydrochloride
中文别名
英文别名 XI-011 hydrochloride;XI-011 HCl;XI-011; XI011; XI011; NSC 146109 HCl; NSC146109; NSC146109;
SMILES CC1=C2C=CC=CC2=C(C3=CC=CC=C13)CSC(=N)N.Cl
化学名称
分子式 C17H17ClN2S 分子量 316.85
纯度 98% 配送 惯例下常温包邮
产品描述 NSC 146109, a small-molecule inhibitor of MDMX, showed robust anti-proliferation activity against several cervical cancer cell lines. XI-011 promoted apoptosis of cervical cancer cells via stabilizing p53 and activating its transcription activity. Moreover, XI-011 inhibited the growth of xenograft tumor in HeLa tumor-bearing mice, as well as enhanced the cytotoxic activity of cisplatin both in vitro and in vivo.
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