环磷酰胺一水物

参考资料仅供科学研究，不可用于个人用途。

货号：BCP22663CAS号：6055-19-2纯度：98%

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CAS号	6055-19-2	货号	BCP22663
中文名	环磷酰胺一水物
英文名	Cyclophosphamide hydrate
中文别名	环磷酰胺一水合物;
英文别名	Cyclophosphamide monohydrate;
SMILES	ClCCN(CCCl)P1(OCCCN1)=O.[H]O[H]
化学名称
分子式	C7H17Cl2N2O3P	分子量	279.1
纯度	98%	配送	惯例下常温包邮
产品描述	Cyclophosphamide hydrate is a synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities.Cyclophosphamide is used as chemotherapy and to suppress the immune system. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. As an immune suppressor it is used in nephrotic syndrome and following organ transplant. It is taken by mouth or injection into a vein. The main effect of cyclophosphamide is due to its metabolite phosphoramide mustard. This metabolite is only formed in cells that have low levels of ALDH. Phosphoramide mustard forms DNA crosslinks both between and within DNA strands at guanine N-7 positions (known as interstrand and intrastrand crosslinkages, respectively). This is irreversible and leads to cell apoptosis.