ODM-203 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP30030CAS号：1430723-35-5纯度：98%

规格	价格(CNY)	是否现货	购买咨询
5.00 mg	￥540.00	In-stock	购买咨询
10.00 mg	￥910.00	In-stock	购买咨询
50.00 mg	￥2650.00	In-stock	购买咨询

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CAS号	1430723-35-5	货号	BCP30030
中文名	ODM-203
英文名	ODM-203
中文别名
英文别名	ODM203;ODM 203;
SMILES
化学名称
分子式	C26H21F2N5O2S	分子量	505.54
纯度	98%	配送	惯例下常温包邮
产品描述	ODM-203 (ODM203) is a potent, selective, dual inhibitor of FGFR and VEGFR tyrosine kinases with approximately equal potency towards recombinant FGFR1, 2, 3 and 4, as well as VEGFR1, 2 and 3 (IC50=5-35 nM); suppresses 9/317 additional kinases by >70% at 1 uM, 9 kinases suppressed by ODM-203 - DDR1, MAP4K4, MINK1, RET, PDGFRa and SIK2 (IC50<100 nM); ODM-203 is a potent inhibitor of FGFR signaling and proliferation in several FGFR-dependent cell lines; ODM-203 inhibits VEGFR-induced tube formation (IC50 33 nM) with similar potency as it inhibits proliferation in FGFR-dependent cell lines (IC50 50-150 nM); inhibits FGFR phosphorylation and tumor growth in several FGFR-dependent xenografts.