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| CAS号 | 197720-53-9 | 货号 | BCP36302 |
| 中文名 | 依喜替康甲磺酸盐二水合物 | ||
| 英文名 | Exatecan mesylate dihydrate | ||
| 中文别名 | |||
| 英文别名 | DX 8951; DX-8951; DX8951; | ||
| SMILES | CCC1(C2=C(COC1=O)C(=O)N3CC4=C5C(CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O.CS(=O)(=O)O.O.O | ||
| 化学名称 | |||
| 分子式 | C25H32FN3O9S | 分子量 | 567.58 |
| 纯度 | 98％ | 配送 | 惯例下常温包邮 |
| 产品描述 | Exatecan Mesylate is a semisynthetic, water-soluble derivative of camptothecin with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues. | ||
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