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| CAS号 | 71439-68-4 | 货号 | BCP46265 |
| 关联产品 | 78186-34-2（比生群） | ||
| 中文名 | 比生群二盐酸盐 | ||
| 英文名 | Bisantrene dihydrochloride | ||
| 中文别名 | |||
| 英文别名 | Bisantrene HCl;CL-216942; CL216942; CL 216942; | ||
| SMILES | C1CN=C(N1)NN=CC2=C3C=CC=CC3=C(C4=CC=CC=C42)C=NNC5=NCCN5.Cl.Cl | ||
| 化学名称 | |||
| 分子式 | C22H24Cl2N8 | 分子量 | 471.39 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Bisantrene is topoisomerase II poisons and DNA intercalators. It may be used as model compounds to study P-glycoprotein-mediated multiple drug resistance (MDR1). Bisantrene may be used as a Rac1 inhibitor. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity. | ||
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