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Snail/HDAC-IN-1 结构式

Snail/HDAC-IN-1

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货号 :BCP48514CAS号 :2415281-52-4纯度:98%
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  • 基本信息与产品描述
CAS号 2415281-52-4 货号 BCP48514
中文名 Snail/HDAC-IN-1
英文名 Snail/HDAC-IN-1
中文别名
英文别名 CYD19;
SMILES CC1=CC(=NN1)NC2=NC(=NN3C2=CC=C3)SCC4=CC=C(C=C4)C(=O)NC5=C(C=C(C=C5)F)N
化学名称
分子式 C24H21FN8OS 分子量 488.54
纯度 98% 配送 惯例下常温包邮
产品描述 Snail/HDAC-IN-1 is a potent Snail/HDAC dual target inhibitor. Snail/HDAC-IN-1 displays potent inhibitory activity against HDAC1 with an IC50 of 0.405 μM and potent inhibition against Snail with a Kd of 0.18 μM. Snail/HDAC-IN-1 increases histone H4 acetylation in HCT-116 cells and decreases the expression of Snail protein to induce cell apoptosis.
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