Encorafenib 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP44104CAS号：1269440-29-0纯度：98%

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CAS号	1269440-29-0	货号	BCP44104
中文名	Encorafenib
英文名	Encorafenib
中文别名
英文别名	LGX818; LGX-818; LGX 818;
SMILES	CC(C)N1C=C(C(=N1)C2=C(C(=CC(=C2)Cl)NS(=O)(=O)C)F)C3=NC(=NC=C3)NCC(C)NC(=O)OC
化学名称
分子式	C22H27ClFN7O4S	分子量	540.01
纯度	98%	配送	惯例下常温包邮
产品描述	Encorafenib is an orally available Raf kinase inhibitor with potential antineoplastic activity. Encorafenib specifically inhibits Raf kinase, a serine/threonine enzyme in the RAF/mitogen-activated protein kinase kinase (MEK)/extracellular signal-related kinase (ERK) signaling pathway. By inhibiting the activation of the RAF/MEK/ERK signaling pathway, the administration of LGX818 may result in a decrease in proliferation of tumor cells. The Raf mutation BRAF V600E is frequently upregulated in a variety of human tumors and results in the constitutive activation of the RAF/MEK/ERK signaling pathway that regulates cellular proliferation and survival.