Vimseltinib 新

参考资料仅供科学研究，不可用于个人用途。

货号：BCP44095CAS号：1628606-05-2纯度：98%

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CAS号	1628606-05-2	货号	BCP44095
中文名	Vimseltinib
英文名	Vimseltinib
中文别名
英文别名	DCC-3014; DCC 3014; DCC3014;
SMILES	CC1=C(C=CC(=N1)C2=CN=C(N(C2=O)C)NC(C)C)OC3=CC(=NC=C3)C4=CN(N=C4)C
化学名称
分子式	C23H25N7O2	分子量	431.49
纯度	98%	配送	惯例下常温包邮
产品描述	Vimseltinib, also known as DCC-3014, is a potent and orally active inhibitor of the tyrosine kinase receptor colony stimulating factor 1 receptor (CSF1R; CSF-1R; C-FMS; CD115; M-CSFR), with potential antineoplastic, macrophage checkpoint-inhibitory and immunomodulating activities. Upon administration, DCC-3014 targets and binds to CSF1R expressed on monocytes, macrophages, and osteoclasts and inhibits the binding of the CSF1R ligands colony-stimulating factor-1 (CSF-1) and interleukin-34 (IL-34), to CSF1R. This prevents CSF1R activation and CSF1R-mediated signaling in these cells. This blocks the production of inflammatory mediators by macrophages and monocytes and reduces inflammation.