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APR-246 结构式

APR-246

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货号 :BCP20294CAS号 :5291-32-7纯度:98%
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  • 基本信息与产品描述
CAS号 5291-32-7 货号 BCP20294
中文名 APR-246
英文名 APR-246
中文别名
英文别名 APR 246;APR246;Prima-1met;
SMILES
化学名称
分子式 C10H17NO3 分子量 199
纯度 98% 配送 惯例下常温包邮
产品描述 APR-246 is a quinuclidinone derivative that targets the Wrap53 gene with potential antineoplastic activity. p53 activator APR-246 binds to and activates transcription of the Wrap53 gene, which results in an increase in WRAP53 p53 antisense transcript levels and, potentially, an increase in native p53 activity; in turn, increased p53 activity may lead to an induction of cell cycle arrest and apoptosis in tumor cells. This agent may work synergistically with other antineoplastic agents.
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