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| CAS号 | 1688673-09-7 | 货号 | BCP34015 |
| 中文名 | TAS-115 mesylate | ||
| 英文名 | TAS-115 mesylate | ||
| 中文别名 | |||
| 英文别名 | TAS 115 methanesulfonate;TAS-115 methanesulfonate;TAS115 mesylate; | ||
| SMILES | CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=C(C=C(C=C3)NC(=S)NC(=O)CC4=CC=CC=C4)F.CS(=O)(=O)O | ||
| 化学名称 | |||
| 分子式 | C28H27FN4O7S2 | 分子量 | 614.66 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | TAS-115 is a c-MET and VEGFR inhibitor which is selective and specific in vitro. In vivo studies, TAS-115 suppressed the progression of MET-inactivated tumor completely through blocking angiogenesis without toxicity and it also induced marked tumor shrinkage and prolonged survival in animal model. In Dec 2013, Phase-I development was ongoing in Japan. In Dec 2014, Taiho Pharmaceutical completed a phase I trial for Solid tumours in Japan. In Apr 2016, preclinical data was presented. | ||
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