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| CAS号 | 682745-41-1 | 货号 | BCP45190 |
| 关联产品 | 475108-18-0（替沃扎尼） | ||
| 中文名 | 替沃扎尼盐酸盐一水合物 | ||
| 英文名 | Tivozanib hydrochloride hydrate | ||
| 中文别名 | 盐酸替沃扎尼一水合物; | ||
| 英文别名 | Tivozanib HCl H2O; | ||
| SMILES | CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl.O.Cl | ||
| 化学名称 | |||
| 分子式 | C22H22Cl2N4O6 | 分子量 | 509.34 |
| 纯度 | 98% | 配送 | 惯例下常温包邮 |
| 产品描述 | Tivozanib is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities. Tivozanib binds to and inhibits VEGFRs 1, 2 and 3, which may result in the inhibition of endothelial cell migration and proliferation, inhibition of tumor angiogenesis and tumor cell death. VEGFR tyrosine kinases, frequently overexpressed by a variety of tumor cell types, play a key role in angiogenesis. | ||
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