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CAS No. | 1033836-12-2 | Cat. No. | BCP27743 |
Name | MDK36122 | ||
Synonyms | MDK36122; MDK-36122; H-PGDS Inhibitor I; Prostaglandin D Synthase (hematopoietic-type) Inhibitor I; | ||
SMILES | C1CN(CCC1NC(=O)C2=CN=C(C=C2)C3=CC(=CC=C3)F)CC(F)(F)F | ||
Chemical Name | |||
Formula | C19H19F4N3O | M. Wt | 381.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MDK36122 is a potent, selective and orally active Hematopoietic Prostaglandin D Synthase (HPGDS) inhibitor with an IC50s of 0.6 nM and 32 nM in enzyme and cellular assays, respectively. HPGDS inhibitor 1 does not inhibit human L-PGDS, mPGES, COX-1, COX-2, or 5-LOX. |
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