GYY 4137 morpholine salt New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 106740-09-4 | Cat. No. | BCP23715 |
| Name | GYY 4137 morpholine salt | ||
| Synonyms | GYY4137; GYY-4137; GYY 4137;ZYJ1122; ZYJ 1122; ZYJ-1122; | ||
| SMILES | COC1=CC=C(C=C1)P(=S)(N2CCOCC2)S.C1COCCN1 | ||
| Chemical Name | |||
| Formula | C11H16NO2PS2.C4H9NO | M. Wt | 376.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GYY4137 is a novel water-soluble and slow releasing H2S donor. Hydrogen sulfide (H2S) is now recognized as the so called "third gasotransmitter" taking its place alongside nitric oxide and carbon monoxide. GYY4137 protects against myocardial ischemia and reperfusion injury by attenuating oxidative stress and apoptosis in rats. GYY4137 inhibits the inflammatory response by suppressing the activation of nuclear factor-kappa B and mitogen-activated protein kinases in Coxsackie virus B3-infected rat cardiomyocytes. GYY4137 exhibits potent anti-cancer activity by releasing H2S over a period of days. | ||
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