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LM10 Chemical Structure

LM10

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31973CAS No. :1316695-35-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1316695-35-8 Cat. No. BCP31973
Name LM10
Synonyms LM 10; LM-10;
SMILES C1=CC2=C(C=C1F)NC=C2C=CC3=NNN=N3
Chemical Name
Formula C11H8FN5 M. Wt 229.22
Purity 98% Storage Store at 4-8°C
Description LM10 is a selective tryptophan 2,3-dioxygenase (TDO) inhibitor (IC50 values are 0.62 and 2 μM for human and mouse TDO, respectively). LM10 exhibits selectivity for TDO over IDO, MAO-A, MAO-B, and a panel of receptors and transporters. LM10 reduces growth of TDO-expressing P815 mastocytoma tumors in mice.
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