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Izuforant Chemical Structure

Izuforant

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP48744CAS No. ：1429374-83-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1429374-83-3 Cat. No. BCP48744
Name Izuforant
Synonyms JW1601;JW 1601;JW-1601;
SMILES CNC1CN(C1)C2=NC3=C(C=C(C=N3)Br)N4C2=NN=C4
Chemical Name
Formula C12H12BrN7 M. Wt 334.17
Purity 98% Storage Store at 4-8°C
Description Izuforant (JW1601) is an orally active histamine H4 receptor (H4R) antagonist with an IC50 of 36 nM against human H4R. Izuforant also shows binding affinity of human serotonin 3 receptor (h5-HT3R) with an IC50 of 9.1 μM. Izuforant exhibits strong anti-pruritic and anti-inflammatory efficacies.
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