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Pemetrexed disodium Chemical Structure

Pemetrexed disodium

Data Sheet For research use only. Not for human use.
Cat. No. :BCP23433CAS No. :150399-23-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 150399-23-8 Cat. No. BCP23433
Name Pemetrexed disodium
Synonyms LY-231514 disodium;Alimta;LY 231514 disodium;LY231514 disodium;
SMILES
Chemical Name
Formula C20H19N5Na2O6 M. Wt 471.37
Purity 98% Storage Store at 4-8°C
Description Pemetrexed disodium is a novel antifolate, the Ki values of the pentaglutamate of LY231514 are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.Pemetrexed is a novel antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM in cell-free assays, respectively.
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