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CAS No. | 171744-42-6 | Cat. No. | BCP44783 |
Name | PD-159206 | ||
Synonyms | DIBA-4; PD159206; PD 159206; | ||
SMILES | CCC(C)C(C(=O)O)NC(=O)C1=CC=CC=C1SSC2=CC=CC=C2C(=O)NC(C(C)CC)C(=O)O | ||
Chemical Name | |||
Formula | C26H32N2O6S2 | M. Wt | 532.67 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PD-159206 is a nucleocapsid inhibitor. It exhibits good antiviral activity against HIV. In T cell culture, the 50% inhibitory concentrations (EC(50)) of PD 161374 was on average 2.5 microM (ranges of 1.2-13.5 microM) without any cytotoxic effect up to 100 microM. PD 161374 inhibited acute HIV infection and it was effective when added during the early phase of HIV infection. PD 161374 exerts its antiviral effect at pre-integration steps in the early phase of the virus life cycle. |
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