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PF-06882961 Chemical Structure

PF-06882961

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31501CAS No. :2230198-02-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2230198-02-2 Cat. No. BCP31501
Related Products 2230198-03-3(Danuglipron tromethamine)
Name PF-06882961
Synonyms PF 06882961;PF06882961;Danuglipron;
SMILES C1CN(CCC1C2=NC(=CC=C2)OCC3=C(C=C(C=C3)C#N)F)CC4=NC5=C(N4CC6CCO6)C=C(C=C5)C(=O)O
Chemical Name
Formula C31H30FN5O4 M. Wt 555.61
Purity 98% Storage Store at 4-8°C
Description PF-06882961 is a potent, orally bioavailable agonist of the glucagon-like peptide-1 receptor (GLP-1R) agonist. PF-06882961 stimulates cAMP accumulation in CHO cells expressing both the human and monkey GLP-1Rs with comparable EC50 values. PF-06882961 shows mild to moderate damage to the heart, moderate to severe effects on the thymus gland (which helps with managing infection), mild to moderate stomach ulcers at the highest dose level given in the rat.
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