
SN-011 New

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CAS No. | 2249435-90-1 | Cat. No. | BCP41129 |
Name | SN-011 | ||
Synonyms | SN011;SN 011; | ||
SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC3=CC(=C(C=C3)O)NS(=O)(=O)C4=CC=C(C=C4)F | ||
Chemical Name | |||
Formula | C25H19FN2O4S | M. Wt | 462.49 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SN-011 is a potent and selective mouse and human STING inhibitor, with an IC50 of 76 nM for STING signaling. SN-011 competes with cyclic dinucleotide (CDN) for the binding pocket of the STING dimer, blocking CDN binding and STING activation. SN-011 can be used for the research of STING-driven autoimmune and inflammatory disease. |
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