MYCi361 New
Data Sheet
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| CAS No. | 2289690-31-7 | Cat. No. | BCP34061 |
| Name | MYCi361 | ||
| Synonyms | MYCi-361;MYCi 361;NUCC-0196361;NUCC 0196361;NUCC0196361; | ||
| SMILES | CN1C(=CC(=N1)C(F)(F)F)C2=C(C(=C(C=C2)OCC3=CC=C(C=C3)Cl)C4=CC(=CC(=C4)C(F)(F)F)C(F)(F)F)O | ||
| Chemical Name | |||
| Formula | C26H16ClF9N2O2 | M. Wt | 594.86 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MYCi361 is a MYC inhibitor with the Kd of 3.2 μM for binding to MYC. MYCi361 (NUCC-0196361) suppresses tumor growth and enhances anti-PD1 immunotherapy.MYCi361 inhibits the viability of MYC-dependent cancer cells including prostate cancer (MycCaP, LNCaP, and PC3), leukemia (MV4-11), lymphoma (HL-60 and P493-6), and neuroblastoma (SK-N-B2) with low-micromolar IC50 values. | ||
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