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Radiprodil Chemical Structure

Radiprodil

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30852CAS No. :496054-87-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 496054-87-6 Cat. No. BCP30852
Name Radiprodil
Synonyms RGH-896; RGH896; RGH 896;
SMILES C1CN(CCC1CC2=CC=C(C=C2)F)C(=O)C(=O)NC3=CC4=C(C=C3)NC(=O)O4
Chemical Name
Formula C21H20FN3O4 M. Wt 397.41
Purity 98% Storage Store at 4-8°C
Description Radiprodil, also known as RGH-896, is an orally active and selective NMDA receptors antagonist which was evaluated as potential treatmen of neuropathic pain associated with diabetic peripheral neuropathy (DPNP). Treatment with radiprodil did not show statistically significant or clinically meaningful reductions in mean daily pain scores, the primary endpoint, compared to placebo for any of the dosages studied. Based on preclinical pharmacology Radiprodil was a potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions.
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