LY2322600 New
Data Sheet
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| CAS No. | 862505-01-9 | Cat. No. | BCP27665 |
| Name | LY2322600 | ||
| Synonyms | LY 2322600;LY-2322600; | ||
| SMILES | CC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O | ||
| Chemical Name | |||
| Formula | C25H33FN6O3S | M. Wt | 516.64 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LY2228820 is a novel and potent p38MAPK inhibitor. In vitro kinase enzyme activity showed that the IC50 for p38αMAPK and p38βMAPK of LY2228820 were 7 nM and 3 nM, respectively. Phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, was significantly inhibited by LY in both MM cell lines and LT-BMSCs. | ||
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