RO-9187 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 876708-03-1 | Cat. No. | BCP46487 |
| Name | RO-9187 | ||
| Synonyms | RO 9187; RO9187; | ||
| SMILES | C1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)O | ||
| Chemical Name | |||
| Formula | C9H12N6O5 | M. Wt | 284.23 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | RO-9187 is a potent inhibitor of HCV virus replication in the replicon system (IC(50) = 171 +/- 12 nM; CC(50) >1 mM). RO-9187 is an excellent substrate for deoxycytidine kinase and is phosphorylated with efficiencies up to 3-fold higher than deoxycytidine. RO-9187 is a new class of antiviral nucleosides with promising preclinical properties as potential medicines for the treatment of HCV infection. | ||
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