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Eliglustat tartrate Chemical Structure

Eliglustat tartrate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28712CAS No. :928659-70-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 928659-70-5 Cat. No. BCP28712
Name Eliglustat tartrate
Synonyms Genz 112638; Genz-112638; Genz112638; Eliglustat hemitartrate;
SMILES CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.CCCCCCCC(=O)NC(CN1CCCC1)C(C2=CC3=C(C=C2)OCCO3)O.C(C(C(=O)O)O)(C(=O)O)O
Chemical Name
Formula C50H78N4O14 M. Wt 959.17
Purity 98% Storage Store at 4-8°C
Description Eliglustat, also known as Genz-112638, is is a potent and selective glucosylceramide synthase inhibitor. Eliglustat was approved for Gaucher's disease. Commonly used as the tartrate salt, the compound is believed to work by inhibition of glucosylceramide synthase. According to an article in Journal of the American Medical Association the oral substrate reduction therapy resulted in "significant improvements in spleen volume, hemoglobin level, liver volume, and platelet count" in untreated adults with Gaucher disease Type 1.
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