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Dorzagliatin Chemical Structure

Dorzagliatin

Data Sheet For research use only. Not for human use.
Cat. No. :BCP20539CAS No. :1191995-00-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1191995-00-2 Cat. No. BCP20539
Name Dorzagliatin
Synonyms Sinogliatin; HMS 5552; HMS-5552; HMS5552; RO5305552; RO-5305552; RO 5305552;
SMILES O=C(NC1=NN(C[C@@H](O)CO)C=C1)[C@@H](N2CC(OC(C=CC=C3)=C3Cl)=CC2=O)CC(C)C
Chemical Name
Formula C22H27ClN4O5 M. Wt 462.93
Purity 98% Storage Store at 4-8°C
Description Dorzagliatin, also known as HMS 5552, RO5305552 and sinogliatin, is a novel Dual-Acting Glucokinase Activator, which Improves Glycaemic Control and Pancreatic β-Cell Function in Patients With Type 2 Diabetes. By addressing the defect of the glucose sensor function of glucokinase, dorzagliatin has the potential to restore the impaired glucose homeostasis state of people with type 2 diabetes and serve as a first-line standard-of-care therapy for the treatment of the disease, or as a cornerstone therapy when taken in combination with currently approved anti-diabetes drugs.
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