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RG7129 Chemical Structure

RG7129

Data Sheet For research use only. Not for human use.
Cat. No. :BCP23733CAS No. :1310347-50-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1310347-50-2 Cat. No. BCP23733
Name RG7129
Synonyms RO5508887; RO-5508887; RO 5508887; RG-7129; RG 7129;BACE1-IN-1;
SMILES O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)OCC3(F)F)=C2
Chemical Name
Formula C18H14F3N5O2 M. Wt 389.33
Purity 98% Storage Store at 4-8°C
Description RG7129 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively.
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