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KN92 Chemical Structure

KN92

Data Sheet For research use only. Not for human use.
Cat. No. :BCP35203CAS No. :176708-42-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 176708-42-2 Cat. No. BCP35203
Name KN92
Synonyms KN 92;KN-92;
SMILES CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC
Chemical Name
Formula C24H25ClN2O3S M. Wt 456.98
Purity 98% Storage Store at 4-8°C
Description KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell.
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