Pactimibe New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 189198-30-9 | Cat. No. | BCP48994 |
| Related Products | 608510-47-0（Pactimibe sulfate） | ||
| Name | Pactimibe | ||
| Synonyms | CS-505; CS505; CS 505; | ||
| SMILES | CCCCCCCCN1CCC2=C(C(=C(C(=C21)NC(=O)C(C)(C)C)C)CC(=O)O)C | ||
| Chemical Name | |||
| Formula | C25H40N2O3 | M. Wt | 416.6 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pactimibe is a dual ACAT1/2 inhibitor with IC50s of 4.9 μM and 3.0 μM, respectively. Pactimibe inhibits ACAT with IC50s of 2.0 μM, 2.7 μM, 4.7 μM in the liver, macrophages and THP-1 cells, respectively. Pactimibe noncompetitively inhibits oleoyl-CoA with a Ki value of 5.6 μM. Moreover, Pactimibe obviously inhibits cholesteryl ester formation with an IC50 of 6.7 μM. Pactimibe possesses anti-atherosclerotic potential with lowering plasma cholesterol activity. | ||
Recommend Products
More >
-
GOAT-IN-1
Cat. No.：BCP49688
No.：1452473-54-9
Product Details -
-
-
-
-
N-Caffeoyl O-methyltyramine
Cat. No.：BCP48927
No.：189307-47-9
Product Details -
-
Zinc protoporphyrin
Cat. No.：BCP48478
No.：15442-64-5
Product Details -
-
-
-
-
-
Pactimibe sulfate
Cat. No.：BCP45168
No.：608510-47-0
Product Details -
-
-
-
PF-06424439 HCl
Cat. No.：BCP43813
No.：1469284-80-7
Product Details -
PF-06424439 Mesylate
Cat. No.：BCP43812
No.：1469284-79-4
Product Details -
Tags:Pactimibe supplier,Pactimibe purchase,Pactimibe manufacturer,Pactimibe distributor,Pactimibe cost,Pactimibe buy,Pactimibe for sale